Arimistane Guide: How to Get the Best Results Using Arimistane


A good Post Cycle Therapy ( PCT) supplement is essential to restoring your natural testosterone levels and support the muscle gains achieved from the pro-hormone or SARM cycle. While most of the PCT products require a prescription, there are quite a few which are available over-the-counter. Arimistane is one of the most popular prescription-free and legal PCT supplements currently available on the market and I personally swear by it both during and after a cycle.

Recovering from a cycle can be very tough on the body, because the testosterone levels can drop significantly. leaving you in a catabolic state. Arimistane comes to my rescue every time, helping to speed up recovery, maintain my muscle mass gains, reduce the estrogen levels and restore my testosterone back to normal.

Read on to find out how you should properly use Arimistane for the best results and how it will help you both during and after a a SARMs or pro-hormone cycle.

What is Arimistane?

In a nutshell, Arimistane is an over-the-counter versatile supplement that can be used as a:

  • muscle growth support supplement
  • estrogen blocker
  • testosterone booster
  • fat burner
  • ergogenic aid (performance enhancer).

Arimistane is a potent, third-generation aromatase inhibitor (AI) and one of the most effective and easily accessible PCT supplements out there. The generic name is Androsta 3,5-diene-7, 17-dione. Aromatase ( AROM) is an enzyme that converts androgen precursors (e.g. testosterone) to phenols, catalyzing a key aromatisation step in the production of estrogen. This is why AIs are commonly known as estrogen blockers or estrogen synthesis inhibitors.

Increased estrogen levels and gynecomastia are two very common side effects after a SARMs or prohormone cycle. Thanks to its powerful estrogen-suppressing properties, Arimistane helps minimize estrogen rebound by blocking estrogen production effectively, quickly, and safely.

Estrogen rebound is hard-earned muscle gains’ worst enemy and occurs when the body converts testosterone into the dreaded estrogen at an enhanced rate, following a cycle with prohormones, T boosters, anabolic steroids or SARMs. The higher the testosterone levels, the higher the estrogen levels, as the body seeks to create a balance of these hormones via the enzyme aromatase.

According to Mayo Clinic,, the use of anabolics, androgens or ergogenic aids to enhance workout performance is one of the risk factors of gynecomastia ( man boobs). Other negative effects of high estrogen levels in men include reduced muscle gains, erectile dysfunction (ED), low sex drive, water retention, increased body fat, fatigue, depression, infertility, and even type 2 diabetes, as explained in this University Health News article

Allowing estrogen rebound to occur is akin to self-sabotage and that’s because it actually sabotages your painstaking lean muscle building efforts and ultimately your goals painfully fast. This is where Arimistane comes into play — Arimistane works by immediately inhibiting the enzyme aromatase that’s responsible for converting testosterone into estrogen.

According to,, Androsta 3,5-diene-7, 17-dione (Arimistane) is a naturally-occurring metabolite of 7-Keto Dehydroepiandrosterone (DHEA), which is why it is also known as 3-deoxy- 7-Keto DHEA ( DHEA is a hormone with testosterone-boosting and anti-aging properties and DHEA supplements can be used in conjunction with aromatase inhibitors).

Arimistane is an irreversible, type I aromatase inhibitor structurally similar to the exemestane, branded as Aromasin, Arimistane is also known as a “suicide AI”, as it permanently binds to the AROM enzyme and causes enzyme inactivation, preventing any estrogen rebound , which results in higher testosterone levels.

According to this 2016 study, third-generation AIs, that also include Anastrozole ( brand name Arimidex), exemestane ( Aromasin) and letrozole ( Femara) have shown superior efficacy in inhibiting the enzyme aromatase (AROM) and thus blocking estrogen synthesis.

In addition to suppressing estrogen production, this AI also significantly reduces the levels of cortisol and body fat. According to Research Gate, high levels of cortisol in the body are associated with catabolic ( muscle losing) effects and increased body fat.

When To Take Arimistane and What Are its Benefits

As noted, Androsta 3,5-diene-7, 17-dione is a versatile supplement that can be used in many different ways. Arimistane effectively blocks the effects of estrogen rebound, known as the muscle gains terminator, while increasing your natural T levels, Therefore, it facilitates an optimal anabolic state that enables you to take your muscle building to the next level and reap the multiple benefits associated with high T and low estrogen and cortisol.

As a result, you will experience multi-beneficial effects such as enhanced gains, increased muscle hardness, definition and vascularity, reduced adipose tissue, improved libido, stamina and performance, among others.

  • Increases Muscle Mass and Strength
  • Boosts Natural Testosterone Levels
  • Blocks Estrogen Synthesis and Combats Estrogen Rebound
  • Reduces Cortisol Levels and Detoxifies the Liver
  • Increases Vascularity and Muscle Hardness
  • Boosts Libido and Improves Stamina and Endurance
  • Enhances Athletic and Sexual Performance
  • Increases Luteinizing Hormone (LH)
  • Reduces Body Fat and Water Retention
  • Shortens Recovery Time and Delays Muscle Fatigue
  • Increases Nitrogen Retention and Energy Levels,
  • Improves Mood, Sleep, Cognitive Function and Self-Confidence

Arimistane can be safely and effectively used both intra-cycle ( during a pro-hormone/SARM/steroid cycle) and post-cycle.

In other words, it can be used both as a PCT supplement or as a standalone natural T booster.

Androsta 3,5-diene-7, 17-dione is most commonly used as a PCT. Some seasoned weight lifters as well as pro-hormone/SARMs users typically take it intra-cycle, I personally recommend using it as a part of a high-quality PCT supplement (such as Alpha AF) post-cycle. That’s because once a cycle has been ceased, your natural testosterone production can be severely affected., while experiencing an unwanted surge in estrogen production.

Arimistane effectively helps you maintain your muscle mass growth and strength levels by boosting your natural testosterone levels and suppressing estrogen synthesis. It will not eliminate estrogen from your body, but it will properly keep it under control. With Androsta 3,5-diene-7, 17-dione immediately blocking estrogen production, you don’t have to worry about losing your hard-earned muscle gains, because it immediately inhibits the enzyme which is responsible for converting T into estrogen.

I recommend using Arimistane as a PCT IMMEDIATELY after a pro-hormone/anabolic steroid/SARM cycle.

Androsta 3,5-diene-7, 17-dione works as an anti-estrogen, so if you notice signs such as man boobs ( gynecomastia), mood swings, water retention, reduced libido, depression and fatigue, you should start taking Arimistane right away. These signs are associated with high estrogen levels, which means that despite your efforts, your body already converts testosterone into estrogen. Alpha AF by Steel Supplements is particularly effective against man boobs, as in addition to Androsta 3,5-diene-7, 17-dione it contains other safe ingredients with estrogen-blocking properties.

Arimistane Standalone

Arimistane also works as a standalone natural testosterone booster. It helps stimulate the pituitary gland to produce more Luteinizing Hormone, thus raising LH. According to WebMD,, the symptoms associated with low LH in men include low T levels, low libido and decreased muscle mass.

When used as a standalone T booster, Arimistane helps optimize the body into a distinctly anabolic environment, so as to support new muscle gains quickly and safely, without estrogen and cortisol getting in the way of your muscle building goals. Arimistane thus ensures that all muscle gains are properly maintained once cycled off steroids, prohormones or SARMs and hormones are optimized for future gains.

This popular hormone optimizer can be used as a standalone by men of all ages who want to increase their natural T levels. Older men that suffer from high estrogen levels can find it beneficial too. With the use of Arimistane, you can quickly turn the tables on your hormones, and reap the many benefits associated with suppressed estrogen production, including reduced adipose tissue especially the stubborn fat in the abdominal area, increased lean muscle mass, improved muscle strength and enhanced libido.

With estrogen out of your way and increased levels of natural testosterone, it will be easier for you to gain muscle mass, boost muscle strength and maximize your performance potential in the gym. The fact that you don’t need a prescription to use Arimistane, unlike other PCT, is also a plus. Additionally, you can conveniently and discreetly purchase it online which can save you both time and money.

Whether you’re using it as part of a PCT supplement or as a standalone T booster, Arimistane is one of the safe, effective, and legal ways to suppress estrogen synthesis without needing a prescription and without the side effects associated with stronger, prescription PCT.

Thanks to its potent estrogen-inhibiting effects, Arimistane is typically the stack for other pro-hormone supplements, helping to enhance their benefits. Consider using Arimistane in the way that best suits your specific needs.

Arimistane Recommended Dosage

if you’ve never used Arimistane before, then you should advisedly start by taking a low dose so you can see its effects on your body. The dosage that is recommended to start out with is 25 mg of Arimistane a day and then gradually build up the dosage to 75 mg per day. Based on my personal experience with Arimistane, it’s safe to say that 75 mg of Arimistane per day is more than sufficient. That’s because Androsta 3,5-diene-7, 17-dione is a highly effective and ultra-potent, third-generation AI and if you exceed the recommended daily dosage, you may inadvertently crash the levels of estrogen in your body.

So the recommended daily dosage for Arimistane is 25 mg -75 mg ( start out with the lower end and then gradually increase the dosage to no more than 75 mg).

Arimistane Side Effects

Little to no adverse effects have been reported by Arimistane users when administered as directed. Whereas androgen replacement therapy such as intramuscular injections with synthetic esters of testosterone ( e.g. testosterone cypionate) have been associated with many side effects as well as an increased risk of heart disease and prostate cancer, this testosterone booster, estrogen blocker and anabolic growth supplement hasn’t been linked to harmful effects, as long as the recommended dose of up to 75 mg a day is not exceeded.

I’ve taken Arimistane several times and experienced no adverse effects, except a bit of nausea and mild headaches, but I am unsure these had anything to do with the use of this supplement.

My Experience with Arimistane

I’ve taken both pro-hormones and SARMs and every time Arimistane has helped me stabilize and restore my T levels, while maintaining my muscle gains. Arimistane is my top favorite PCT supplement because it’s very potent and works fast, has little to no side effects and it’s affordable, legal, and very easy to get online.

I prefer this over-the-counter yet extremely potent PCT supplement to drugs that require a prescription such as tamoxifen ( brand name Nolvadex) and clomiphene citrate ( brand name Clomid). The reason is that both pro-hormones and SARMs are quite mild and not too suppressive, when compared to anabolic steroids, so a PCT supplement such as Arimistane will do the trick.

Unless you’re using very strong anabolic steroids, Arimistane is more than sufficient as a Post-Cycle Therapy, as it’s extremely powerful but without the side effects associated with Clomid and Nolvadex ( which include mood swings and visual problems). Even better, you don’t need a prescription for Arimistane. after a pro-hormone or SARM cycle.

I always use Alpha-AF,, a top-quality PCT supplement manufactured by Steel Supplements, because in addition to an optimal concentration of Androsta 3,5-diene-7, 17-dione, it also contains other potent PCT ingredients (i.e. Byroviron, DHEA and 5-Alpha-Hydroxy-Laxogenin) to speed up recovery, inhibit estrogen synthesis and boost T levels.

Best Arimistane Formulas

There are quite a few Arimistane supplements currently available on the market, but my favorite by far is Alpha AF., created by Steel Supplements. This innovative formula made in the US and backed by science helps support healthy T levels, acts as an anti-estrogen and promotes fat loss.

If you’ve never used Alpha AF before, you will want to start with just 1 tablet in the morning, ( it’s essential to take it WITH food) and then work your way up to 3 tablets, once a day, with food. For optimized performance and recovery, it’s best to use it for 30 days. Alpha AF is definitely one of the best formulas for PCT currently available on the market.