C4 Pre Workout from Cellucor – all the details

C4 Pre Workout

If you are interested in all the details of C4 pre workout from Cellucor, you might want to read my latest post on the best pre-workout as well. C4 is a good, tried and tested pre-workout, but it’s not the only supplement in town.

C4 from Cellucor is a pre-workout  that has been on the market for years now. The first version came out just around the same time as Jack3d. It didn’t take long before this became one of the most popular pre-workout supplements on the market and known to give you a very potent energy boost.

Since the first version, Cellucor has released several different versions, and I will try to cover all the details on all of them, in this post.​

I have written about C4 and all the C4 variations here on muscles.zone before. Because of this, I have received a bunch of emails with questions about this supplement. In this post, I want to share some of these questions and my answers to them. If you got any questions not listed here, feel free to send me an email so I can add them in.​

How many Different versions of C4 is there?

Let me try to sum things up here the best I can.​

C4 Extreme – Original​

The original C4 with DMAA – This does not seem to be sold anywhere anymore. Your best shot might be e-bay.​

It was out on the market around the same time with all the other popular DMAA based pre-workout supplements; Jack3D, 1MR, etc.

It was also discontinued around the same time as the others. This is now years ago, so inventories are not what they have been. Personally, I haven’t seen the original C4 Extreme anywhere for a number of years now.

C4 Extreme

The second version of C4 which had a similar design to the fist version, the same name and almost the same substances. The main difference here is that the second version didn’t contain DMAA, and the caffeine content was bumped up a notch. Clearly a lot of people mistakenly bought this version, believing they would be getting the DMAA-based version. The exact same thing happened with the other brands; keeping the name, design and supplement facts so close to the original, just with the removal of DMAA, that it was difficult to spot unless you looked close; meaning a lot of people purchases in ignorance.

C4 4th Gen​

There might have been one in between the second version of C4 and this new c4 formula, considering the name of the supplement. However, to my knowledge, this is actually the third version of C4, although it’s named C4 4th Generation.

This version of C4 is very similar to the former version. The main difference here is the addition of TeaCor.

In addition to this, the design has completely changed (for the better), the name is new, and there are new C4 alternatives based on this version. A very interesting move from Cellucor.

C4 50X​

This is exactly the same as C4 Gen. 4 (the one listed above), just with 50% more of each substance used.​

C4 Ripped​

This is a variation of the C4 4th gen. with a touch of fat burner substances added into the mix- a c4 thermogenic or C4 weight loss mix if you will. This is for those who need are looking to shread some pounds while getting a pre-workout with some solid energy boosting substances.

This mix is named the C4 Ripped Blend which is a 1 gram prop. blend of the following substances:

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  • L-Carnitine Tartrate
  • Green Coffee Bean Extract
  • Capsimax
  • Coleus Forskohlii


C4 Mass

This is also a variation of the C4 4th Gen. As the name indicates, this is a pre-workout supplement for those who are looking to bulk up. Don’t confuse this with any sort of weight gainer cause it certainltly isn’t.

This pre-workout comes with what Cellucor calls a Creacarb Blend which contains 27.5g of

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  • polydextrose
  • Fructose
  • Dextrose
  • Sucrose
  • Micronized Creatine Monohydrate.​


C4 Neuro

C4 Neuro is the final and latest C4 4gen. variation. It is partially a nootropic supplement with a focus on giving you energy for your workout while also boosting cognition.

It comes with all the same substances at the C4 4th gen. + the following C4 Neuro Blend which contains 665mg of the following mind boosting substances:

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  • Acetyl-L-Carnitine HCI
  • AlphaSize® A-GPC (Alpha-Glyceryl Phosphoryl Choline)
  • Zembrin® (Sceletium tortuosum) aerial parts extract
  • Toothed Clubmoss (Huperzia serrata) aerial parts extract (standardized for Huperzine A)


Currently, you might be able to find the second version of C4 here and there, but most stores only carry the 5 new C4 4th generation pre-workouts. There are lot’s of options to choose from so let’s continue to break all the details down.

C4 Serving Size​

First of all, you might be able to get a free sample from your local store. In addition to this, you can get it in the following jar sizes:

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  • C4 – 5 servings
  • C4 – 30 servings
  • C4 – 60 servings


C4 Pre Workout Price

How much does c4 cost? The C4 price is usually listed just around $1 per serving, but this fluctuates a bit, depending on where you purchase it, when, which jar size and what version of C4. You will get the cheapest C4 pre workout by purchasing the largest jar size (60 servings). If you purchase a 60 servings jar from bodybuilding.com you will currently get it for $50 meaning that the price per serving comes down to just $0.83. If you want to test it before purchasing a whole jar, check with your local store if they have any c4 pre workout samples.​

Where Can I Buy C4 Pre Workout​

Due to the popularity of this pre-workout supplement, you can get it almost every single supplement store out there. Chances are, they have at your local store as well. However, if you want the cheapest price, you probably want to purchase C4 online. Keep in mind that prices change all the time. Below is a list with the most recent prices from Bodybuilding.com, Suppz, TigerFitness and Amazon.

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C4 Pre Workout Flavors

There is quite the range of different c4 flavors. The best C4 flavor is very subjective but I personally always prefer to go for the more sour options.At the moment, you can get C4 with the following flavors:​

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  • C4 Pre Workout – Blue Raspberry
  • C4 Pre Workout – Fruit Punch
  • C4 Pre Workout – Icy Blue Razz
  • C4 Pre Workout – Watermelon
  • C4 Pre Workout – Strawberry Margarita


C4 Supplement Review

​As mentioned in the beginning, I have several c4 reviews here on muscles.zone. In these reviews, I highlight the details of the supplements, breaking down substance details, potentiel side effects, etc. Being an extremely popular pre-workout, you can also find C4 preworkout reviews on other sites around the web.

C4 from Cellucor: Review

NO Xplode vs. C4

C4 Ripped vs. C4 vs. C4 50X

C4 vs. C4 50X

Cellucor C4 4th. Generation

The above listed posts are full posts with details on substances, effects, side effects, etc. The below listed comparisons are exactly that – each supplement lined up, next to one another for easy comparison of the substances used.

C4 vs. C4 50X

C4 Mass vs. C4 Neuro

C4 50X vs. C4 Neuro

C4 vs. C4 Neuro​

C4 50X vs. C4 Mass​

C4 vs. C4 Mass​

c4 pre workout creatine

Some people are seemingly confused about C4 and it’s creatine content.First of all, it is possible to get C4 without creatine; the C4 Ripped version does not contain creatine. All the other variations are C4 with creatine.

Do not mistake this for a creatine supplement; people have asked me, is C4 creatine? The short answer to that is no, but it does contain creatine along with a bunch of other substances.

Can I get C4 without creatine?

Yes – C4 Ripped does not contain cratine.

Does C4 contain creatine?

Yes. C4, C4 Neuro, C4 50X and C4 Mass all have creatine in them.

How much creatine is in C4?

C4 contains 1 gram. C4 50X has 1.5 g and C4 Neuro has 1 gram. C4 Mass 1 gram of Creatine nitrate and some creatine monohydrate as well; I can’t say exactly how much creatine monohydrate as it is part of a partial prop. blend, but I assume it’s around 3 grams.

What kind of creatine is in C4?

There is creatine nitrate in C4; all of them execpt for C4 Ripped. In addition to this, there is also Creatine monohydrate in C4 Mass.​

C4 Caffeine​

How Much Caffeine is in c4 is a common question as well. There is 160 mg of caffeine in the standard C4 4th gen version and the following in the variations:

C4 Mass: 150 mg

C4 Neuro: 150 mg

C4 50 X: the exact dosage isnt listed but I assume its 225 mg

Keep in mind that the C4 caffeine content is just part of the equation here as TeaCor has many similarities to caffeine so dont let the caffein figure along, fool you.​

Ingredients in C4 Pre Workout​

There is more to C4 than creatine and caffeine. But exactly what is in the C4 Pre Workout supplement, and the different variation?Below you will find a list of the C4 pre workout nutrition facts, or supplement facts, for each of the C4 pre workout supplements that are currently being sold. Below this list with the ingredients in C4, you will find the C4 Pre Workout Nutrition label.​

C4 extreme ingridients

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  • Serving size: 1 scoop (6g)
  • Beta Alanine1500mg
  • Creatine Nitrate1000mg
  • Arginine AKG1000mg
  • Vitamin C (as Ascorbic Acid) 250mg
  • L-Tyrosine200mg
  • Caffeine160mg
  • Bitter Orange (Citrus Aurantium)(Fruit)(30% Synephrine)(Advantra Z)50mg
  • Niacinamide30mg
  • Folate (as Folic Acid) 150mcg
  • Pyridoxal 5-Phosphate35mcg
  • Vitamin B12 (as Methylcobalamin)20mcg


C4 Nutrition Facts

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  • Serving Size: 1 Scoop (6.5g)
  • Vitamin C (as Ascorbic Acid)250 mg417%
  • Niacin (as Niacinamide)30 mg150%
  • Vitamin B6 (as Pyridoxal-5-Phosphate)500 mcg25%
  • Folic Acid250 mcg62%
  • Vitamin B12 (as Methylcobalamin)35 mcg583%
  • Calcium37 mg4%
  • Beta Alanine1.6g†
  • Creatine Nitrate (NO3-T™)1g†
  • Arginine AKG1g†
  • Explosive Energy Blend371mg†
  • Caffeine Anhydrous (160mg)
  • L-Tyrosine
  • TeaCor™ Tetramethyluric Acid


C4 50X Supplement Facts

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  • Serving Size: 1 Scoop (9g)
  • Vitamin C (as Ascorbic Acid)375 mg625%
  • Niacin (as Niacinamide)45 mg225%
  • Vitamin B6 (as Pyridoxal-5-Phosphate)750 mcg37%
  • Folic Acid375 mcg93%
  • Vitamin B12 (as Methylcobalamin)52.5 mcg875%
  • Calcium24 mg2%
  • Beta Alanine2.4g†
  • Creatine Nitrate (NO3-T™)1.5g†
  • Arginine AKG1.5g†
  • C4 50x™ Explosion Blend557mg†
  • N-Acetyl L-Tyrosine
  • Caffeine Anhydrous
  • Velvet Bean (Mucuna Pruriens) seed extract (standardized for L-Dopa)
  • XCELICOR™ Caffeine Pterostilbene Cocrystal
  • TeaCor™ Tetramethyluric Acid


C4 Ripped Supplement Facts

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  • Serving Size: 1 Scoop (6g)
  • Vitamin C (as Ascrobic Acid)250 mg417%
  • Niacin (as Niacinamide)30 mg150%
  • Vitamin B6 (as Pyridoxal-5-Phosphate)500 mcg25%
  • Folic Acid250 mcg62%
  • Vitamin B12 (as Methylcobalamin)35 mcg583%
  • Calcium16 mg2%
  • Beta Alanine1.6g†
  • Arginine AKG1g†
  • C4® Ripped Blend1g†
  • L-Carnitine Tartrate
  • Green Coffee Bean Extract (Standardized for Chlorogenic Acids)
  • Capsimax® Cayenne (Capsicum annuum) fruit extract
  • Coleus forskohlii root extract
  • Explosive Energy Blend371mg†
  • N-Acetyl-L-Tyrosine
  • Caffeine Anhydrous (150mg)
  • Velvet Bean (Mucuna pruriens) seed extract (Standardized for L-Dopa)


C4 Neuro Supplement Facts

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  • Serving Size: 1 Scoop (7.25g)
  • Vitamin C (as Ascorbic Acid)250 mg417%
  • Niacin (as Niacinamide)30 mg150%
  • Vitamin B6 (as Pyridoxal-5-Phosphate)500 mcg25%
  • Folic Acid250 mcg62%
  • Vitamin B12 (as Methylcobalamin)35 mcg583%
  • Beta Alanine1.6g†
  • Creatine Nitrate (NO3-T™)1g†
  • Arginine AKG1g†
  • C4 Neuro™ Blend665mg†
  • Acetyl-L-Carnitine HCI
  • AlphaSize® A-GPC (Alpha-Glyceryl Phosphoryl Choline)
  • Zembrin® (Sceletium tortuosum) aerial parts extract
  • Toothed Clubmoss aerial parts extract (standardized for Huperzine A)
  • Explosive Energy Blend350mg†
  • N-Acetyl-L-Tyrosine
  • Caffeine Anhydrous (150mg)
  • TeaCor™ Tetramethyluric acid


C4 Mass Supplement Facts

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  • Calories70
  • Total Carbohydrate25 g8%**
  • Dietary Fiber11 g44%**
  • Sugars13 g†
  • Vitamin C (as Ascrobic Acid)250 mg417%
  • Niacin (as Niacinamide)30 mg150%
  • Vitamin B6 (as Pyridoxal-5-Phosphate)500 mcg25%
  • Folic Acid250 mcg62%
  • Vitamin B12 (as Methylcobalamin)35 mcg583%
  • Calcium25 mg3%
  • Creacarb™ Blend27.5g†
  • Polydextrose
  • Fructose
  • Dextrose
  • Sucrose
  • Micronized Creatine Monohydrate
  • Beta Alanine1.6g†
  • Creatine Nitrate (NO3-T™)1g†
  • Arginine AKG1g†
  • Explosive Energy Blend371mg†
  • N-Acetyl-L-Tyrosine
  • Caffeine Anhydrous (150mg)
  • Velvet Bean, (Mucuna pruriens) seed extract (standardized for L-Dopa)
  • TeaCor™ Tetramethyluric acid


C4 Pre Workout Label

Now with the supplement facts for all the different versions of C4 listed above, there really shouldnt be a need for this, but I know some of you prefer to see the real thing. Because of this, I have listed images of the actual C4 labels below. ​

C4 Neuro label


C4 label


C4 Ripped label


C4 Mass label


C4 50X label


C4 Extreme label


what is C4 pre workout

So with all this information on the substances used in C4, what exactly is C4? C4 is a pre-workout supplement that. It being sold in jars as a powder which you mix with water, to give yourself a nice C4 drink that will do a couple of things to you: give your more energy, focus and better pumps, when you hit the gym. All the C4 supplements have their own certain angle. The C4 50X is simply stronger than the standard C4 4th gen, but besides from this, it is exactly the same. The C4 neuro has a prop. blend that is said to give a cognitive boost and improve focus even more. C4 Mass is stuffed with additional carbs and creatine monohydrate.

How does C4 work​

How does c4 pre workout work? Basically it does what it does because of the combination of the substances used in the supplement. Some of these does certain things individually while some of them work togehter in synergy as well. They all have energy, focus or pump enhancing properties. Below is a list of all the substances and how they work.

c4 supplement ingredients​ – list of substances———————————————————-

​What does C4 do

As you can tell from the list of substances, all the c4 workout supplement will give you enhanced energy, focus and pumps, for that upcoming workout session. The current C4 4th generations won’t give you as much energy as the former c4 extreme pre workout, as the new versions don’t contain any DMAA, but they will still give you a good surge of energy.

C4 pre workout results

It is a typical for mistake for bodybuilding newbies, to expect that a supplement is what will make the difference to your muscle building efforts – this isnt the case and you shouldnt expect magical C4 results either. I often get asked “is C4 a good pre workout” or “does C4 pre workout work?” – This all depends on where your expectations are. Is C4 pre workout any good? It all depends on what you expect from it, how tolorent to stimulants you are, your size, how you use C4, how many scoops you take, when you take it, etc.

3 scoops of C4 is likely to be overkill and do more harm than good, but 2 scoops migt be your sweet spot to get a solid boost of energy, where as one scoop might not do you any good. Is different from person to person.With that being said, you should naturally always follow directions as listed on the lable and dont ever take more than the max. recommended dose.

​C4 pre workout side effect

Side effects of C4 was a valid concern with the C4 Extreme that contained DMAA. C4 Extreme side effects were definitely an potentiel issue to keep in mind.

​In April 2013, the US Food and Drug Administration determined that methylhexanamine was potentially dangerous and did not qualify as a legal dietary supplement; it warned supplement makers that it was illegal to market methylhexanamine and warned consumers of potentially serious health risks associated with methylhexanamine-containing products.[2][48] The FDA has issued warning letters to manufacturers and distributors who continued to market products containing methylhexanamine.

Back in the days with the DMAA version, side effects of C4 pre workout was a potential issue. There have been death reports related to the use of DMAA, although they have been debated and criticized for being too subjective and one-sided. There have, to my knowledge, never been any C4 pre workout death related stories, but there cases of DMAA containing supplements causing death (read more here). After a period, C4 pre workout got banned, or more correctly, discontinued, after the FDA sent out a warning letter to all supplement manufacturers, creating and selling supplements containing DMAA.

Not only did the old C4 Pre workout come with potential health risks and dangers, but it was also likely to flag you on a drug test, considering the chemical structure of DMAA being somewhat similar to that of amphetamines.

So is C4 Extreme bad for me?

Well it all depends. To put it differently, it’s probably not good for you, but if you kept with dosing within recommendations, you probably would see any significant side-effects. However, since the original C4 Extreme with DMAA isnt being sold anymore, this should be too much of a concern.

New C4 Supplement Side Effects

So what about the new C4 4th generation. Are the new C4 pre-workout supplements safe, bad for you or good for you? Let’s break down the substances and see what side-effects they have, in order to determine the pros and cons of the new C4 Pre-Workout.​

Beta Alanine – Side Effects

Beta-alanine supplementation can cause paresthesia, a potentially uncomfortable but harmless tingling of the skin that normally affects the face. This is similar to the infamous niacin flush. Some people consider this a bad side effect and others don’t. Personally, I don’t think of this as a bad side-effect.​

Creatine Nitrate – Side Effects

There is definitely limited scientific studies on this to conclude it is superior to normal creatine monohydrate. With that being said, creatine has been proven safe over and over again. Nitrates can give you some headache and potentially lower your blood pressure, but if you stay within the recommended servings, this shouldn’t be of any concern.​

Arginine AKG – Side Effects

An energy and pump enhancing substance with very few side-effects reported over the years. Studies from New York University supposedly show that doses of 20 g / daily presented no adverse effects except for minor gastrointestinal issues. It stimulates the production of acids in the stomach and may have an effect on potassium levels. But that’s about it, at this point.​

​Caffeine Anhydrous – Side Effects

A solid energy and performance enhancing substance proven safe and efficient over and over again. Too much of this stuff can give you some jitters, but that’s about it. 150 – 160 mg which you will find in C4, C4 Neuro and C4 Mass probably make you jittery, but the 225 mg in C4 50X might; this all depends on your tolerance level.

L-Tyrosine – Side Effects

There is some speculation this might worsen a migraine for people already exposed for this type of headache. In addition to this, there are a couple of other things to note;

L-tyrosine has several theoretical interactions where caution is warranted. It may raise thyroid hormone production since it is a precursor for its synthesis, so those with a hyperactive thyroid should be wary. Also, it may interact with MAOIs leading to a hypertensive crisis. Additionally, it could theoretically block the uptake from the gut of some drugs that resemble certain amino acids such as levodopa. Finally, since it is a precursor for stimulatory neurotransmitters, it may interact with or potentiate the effects of other drugs or supplements that are stimulatory as well, along with drugs that affect dopamine and norepinephrine productions – Examiner.com

TeaCor™ Tetramethyluric Acid – Side Effects

This is structurally very similar to caffeine and the same is true for the effects.​

​Additional Ingridients in C4 Neuro

​Acetyl-L-Carnitine HCI – Side Effects

​This is a popular brain boosting substance often seen in nootropic stacks. There is no sign of adverse effects when you stay within the recommended limits.

AlphaSize® A-GPC (Alpha-Glyceryl Phosphoryl Choline) – Side Effects

Another brain booster often used in nootropic stacks, but also in other pre-workout supplements (pre-jym for one). From a nootropic perspective, it does appear to have cognitive-promoting properties. There are to the best of my knowledge, not observed any adverse effects from the use of Alpha-GPC.

Zembrin® (Sceletium tortuosum) aerial parts extract – Side Effects

A cognition booster, that may also reduce stress and anxiety. Although the studies on this stuff are limited, there has been no significant side-effect reported.

Toothed Clubmoss aerial (standardized for Huperzine A) – Side Effects​

This is a popular substance in nootropic stacks and becoming increasingly popular in pre-workout supplements as well. It has been shown to have cognitive enhancing properties. According to examiner.com there is no study showing any significant bad side-effects as a result of supplementing with this substance.

Additional Ingridients in C4 Ripped

Carnitine Tartrate​ – Side Effects

ALCAR is covered above as a substance used in C4 Neuro for it’s cognitive enhancing properties. L-Carnitine L-Tartrate is another version of the same, used in C4 Ripped, due to it’s performance and power output enhancing properties. The side-effects from LCLT is seemingly the same as for ALCAR, namely that there is no sign of adverse effects when you stay within the recommended limits.

Green Coffee Bean Extract (Chlorogenic Acids) – Side Effects​

Chlorogenic Acids shows many beneficial properties in relation to health and cognition and shares some effects similar to Caffeine but less potent (one-third). There is a lack of scientific studies on Chlorogenic Acids but from what we know so far, there are no observed side effects.

Capsimax® Cayenne (Capsicum annuum) fruit extract – Side Effects​

A very common substance in fat burners, that has been shown to increase energy expenditure and oxygen consumption rate, with no significant side-effects reported.

​Coleus forskohlii root extract – Side Effects

The bioactive ingredient in Coleus forskohlii is called forskolin. Forskolin has been shown to increase cellular levels of cyclic adenosine monophosphate (cAMP). Elevated cAMP levels are associated with increased rates of fat loss, and can improve the effects of other fat burning compounds. It has been shown that supplementing with Coleus forskohlii can lead to an increase in stomach acid levels, but besides from this, there are no other significant noted side effects.

Additions in C4 Mass:

Carbs and Creatine monohydrate, all of which has been proven safe. There is no need to worry about this stuff.

Additions in C4 50X

There are no additional substances used in this version of C4. There is just more of the same stuff that you will find in C4.

c4 pre workout for women

Some of these substances might not be good for you if you are pregnant or planning to. Besides from this, following directions with C4 should be just as safe for females as for men.

Please do keep in mind that this is merely my take on this. You should no rely on this as advices. Consult with your own doctor, to make sure you know what you are doing.

With that being said, I think it’s fair to say that the new C4, C4 50X, C4 Ripped, C4 Mass and C4 Neuro should be safe supplements for most people out there. I will even go as far as to say that this not only is this likely to give you a better workout but C4 might also be good for you, from a health perspective. Based on the breakdown of the substances above, the benefits of c4 pre workout is seemingly more than just energy.

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